Under the new context and the government’s direction for the Mekong Delta, Can Tho University has established and operated the platform “Sustainable Development of the Mekong Delta, Outlook to 2045 – SDMD 2045” (sdmd2045.ctu.edu.vn) since 2022. Various activities have been carried out during the last two years, with significant achievements under the strong support of government, industry, institutional, and international partners.